A collection of master's theses from the Biological Sciences program in the Department of Natural Sciences and Mathematics at Dominican University of California.

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Theses/Capstones from 2025

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An Evaluation of Bioactive, Sponge-Derived, Marine Natural Products Used Against Triple Negative Breast Cancer and the Malaria Parasite, Plasmodium falciparum, Sofia Odron

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Investigating Mitochondrial Proteins’ Function in Mitoribosome Assembly and Nucleoid Dynamics in S. cerevsiae Utilizing Fluorescent Imaging, Mariko Wayne

Theses/Capstones from 2024

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The Impact of Mutant Protein Disulfide Isomerase A3 and p21-Positive Cell Clearance on Cognitive Function in Mouse Models, Harrison Baker

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Advanced Spatial Analysis of Neural Targets Using Light Sheet Fluorescence Microscopy and Spatial Proteomics, Joshua Brindley

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Investigating the mechanism of action of a highly potent haloalkoxyacridone against Plasmodium falciparum, Jordan Charlton

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New Breast Cancer Drugs Mediate Epigenetic Silencing of ERBB2 via the RNA Exosome, Ana M. Escalante

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Evaluation of the Mycothiazole Chemotype as a Chemical Probe to Study Aging Reveals a New Diastereomer, Joe Gerke

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Exploring the Role of Mitochondrial Fission Factor (MFF) in Murine Reproduction, Wendy Jara

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Deciphering the Complex Networks of Aging Through a Glycation Lowering Tool and the Effects of Methylglyoxal (MGO) on Adipocytes, Edgard Morazan

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Formation of Environmentally Persistent Free Radicals on the Surface of Iron Oxide and Interior of Montmorillonite Clay, Reuben Oumnov

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Investigating the Role of Glycation Stress on Muscle Function and Quality in Aged Mice, Karishma Kamlesh Patel

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Screening effectiveness of compounds for delay of Alzheimer’s Disease pathogenesis in Caenorhabditis elegans and mammalian cell culture, Brielle Rapsas

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Advancing Translational Research in Neurodevelopmental Disorders using a Human Neuronal Xenograft (HuNeuX) Model, Lizet Reyes Rodas

Theses/Capstones from 2023

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Identification and Characterization of Novel Senescent Cell Biomarker and Age-Dependent Functional Decline Innate Immune Cells in Mice, Ashley Brauning

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Investigating the structural changes of glycosaminoglycan polysaccharides in Duchenne Muscular Dystrophy, John Camp

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Investigating the therapeutic effect of glycation-lowering compounds on murine models of menopause-induced Alzheimer's Disease, Lizbeth Enriquez Najera

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Comprehensive investigation of the role of CD38 in ovarian NAD+ metabolism and reproductive aging, Lauren Haky

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An Investigation of The Dominant-Negative Effect of Multiple HAE Type I, SERPING1 Mutations Through In Vitro Model(s), Nicole Hernandez

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Detection and Capture of Nitrogen Fixing Bacteria From Soil and Roots Using Plant Specific Lectins, Alana Horton

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A Mechanistic Evaluation of Naturally Occurring IGF1R 3’UTR Gene Variants Altering Disease Outcomes in Women, Theron Niel

Theses/Capstones from 2022

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Small Molecule Compound with Indole Moiety Protects Against Alzheimer’s Disease Pathology in C. elegans and Mammalian Cell Culture Models, Elena Battistoni

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Exploring the Diet Dependent Role of Oxidation Resistance 1 in regulating Retromer function, Enrique Carrera

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Techniques to Analyze the Pathophysiology of Aging from Induced Senescence and SOD2 loss, Asia Davis-Castillo

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Investigating Transcriptomic and Embryonic Differences Between Cave and Surface Populations of Asellus aquaticus, Haeli Lomheim

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Uncovering the Role of Progranulin in Ameliorating Lysosomal Storage Disease, Angelina Malagodi