Theses/Capstones from 2021
Determining the role of methylglyoxal (MGO) and the TRPA1 channel in inducing astrocyte senescence and neurodegeneration, Natalie Hill
Fungi Associated with Herbaceous Plants in Coastal Northern California, Greg Huffman
Mechanisms of how diet and light interact to influence Drosophila longevity through the eye, Charles H. Lau
Advancing the Preclinical Development of Secondary Metabolites from Cacospongia mycofijiensis for the Treatment of Cancer, Joseph Morris
Investigating the Human-mouse Interspecies Barrier to AAV-driven Gene Therapy Using a Mouse with a Humanized Liver, Slesha Thapa
Theses/Capstones from 2020
Neuroprotection against Alzheimer’s and lifespan extension induced by dietary restriction are associated with metabolomic changes and depend on oxidative resistance protein 1 (OXR1), George W. Brownridge III
Identifying New Markers and Mechanisms of Mitochondrial Defect During Aging, Catherine Chang
Elucidating the Effects of Glucose Toxicity on Tauopathy and Aging, Lukas Fluitt
Model Characterization of Pulmonary Arterial Hypertension: Analysis of Lung Pathology with Respect to Human Disease, Eptisam Lambu
Modulating Matrix Metalloproteases and Inflammation in Huntington’s Disease, Alejandro Lopez Ramirez
NF-L as a Readout for Disease Progression and Rescue, Isaac Villalpando
Determining the link between advanced glycation endproducts (AGEs), feeding, and metabolism, Lauren Wimer
Theses/Capstones from 2019
Characterizing the sphingosine kinase and sphingosine-1-phosphate pathway in pulmonary arterial hypertension, Alyssa Lanza
Biophysical Stability Investigation of Viral Capsids Used for Gene Therapy, Nicole L. McIntosh
Dietary restriction enhances circadian amplitude and delays visual decline by a clock-driven increase in phototransduction, Geoff Meyerhof
Investigating neuroinflammation and demyelination in the nervous system of Twitcher mice by the use of immunohistochemistry, Irene Wilson
Theses/Capstones from 2018
Identification of substrate-selective histone deacetylases and their inhibitors that mediate HER2 transcript stability, Mariah Alejo
Targeting Mitochondrial Proline Dehydrogenase (PRODH) with a Suicide Inhibitor as a Novel Anticancer Strategy, Beatrice Becker
Chronic cadmium exposure alters ERα dependency and drug sensitivity of breast cancer cells, Mathew Bloomfield
Determination of ADAMTS13 Susceptibility in Type IIA von Willebrand Disease, Monica Buselli
Best Practices in a Clinical Development Project Management Office (PMO) to Achieve a Reference Standard in the Pharmaceutical Industry, Russell Guinto