Theses/Capstones from 2019
Biophysical Stability Investigation of Viral Capsids Used for Gene Therapy, Nicole L. McIntosh
Dietary restriction enhances circadian amplitude and delays visual decline by a clock-driven increase in phototransduction, Geoff Meyerhof
Investigating neuroinflammation and demyelination in the nervous system of Twitcher mice by the use of immunohistochemistry, Irene Wilson
Theses/Capstones from 2018
Identification of substrate-selective histone deacetylases and their inhibitors that mediate HER2 transcript stability, Mariah Alejo
Targeting Mitochondrial Proline Dehydrogenase (PRODH) with a Suicide Inhibitor as a Novel Anticancer Strategy, Beatrice Becker
Chronic cadmium exposure alters ERα dependency and drug sensitivity of breast cancer cells, Mathew Bloomfield
Determination of ADAMTS13 Susceptibility in Type IIA von Willebrand Disease, Monica Buselli
Best Practices in a Clinical Development Project Management Office (PMO) to Achieve a Reference Standard in the Pharmaceutical Industry, Russell Guinto
Loss of function of Gene X protects against α-dicarbonyl stress through the skn-1 pathway in C. elegans, Austin Lim
Preclinical Evaluation of Matrix Metalloproteinase Inhibitors and Protein Kinase C Activators in Cell and Mouse Models of Huntington’s Disease, Kuruwitage Madushani
Hypophosphatemic Rickets: A Targeted Literature Review to Characterize the Multiple Causes of Phosphate Wasting Disorders and Identify Potential Disease Biomarkers, Christopher O'Mara
Combinational Therapy to Mitigate α-Dicarbonyl Toxicity, Jessica Ramirez
Theses/Capstones from 2017
Mammalian Cell Line Development Platform for Recombinant Protein Production: Expanding the Protein Expression Toolbox for Research and Drug Discovery Applications, Elizabeth Del Greco
The Developmental and Genetic Basis of Differences in Cave and Surface-dwelling Forms of the Crustacean, Asellus aquaticus, Hafasa Mojaddidi
Modeling 3D Retinogenesis in Mouse Embryonic Stem Cells Following CRISPR-mediated Crx Knockdown, Pooja Prasad
Changing Antimalarial Drug Sensitivities in Uganda, Stephanie Alexis Rasmussen
Novel effects of Prefoldin Pathway on Intestinal Homeostasis via Dietary Restriction in Drosophila melanogaster, Jesse Simons
The Effects of Various Therapeutics on Cystine Stone Formation, See Yang
Theses/Capstones from 2016
Transgenerational epigenetic inheritance via environmental stress in Caenorhabditis elegans, Monica A. Arroliga
Evaluating the Performance of in Silico Predictive Models on Detecting Splice-altering Variants, Erica Cayton
Optimizing Pharmacological Lifespan Extension: Testing Chemical Compounds for Additive Effects on Longevity, Elizabeth Chao
Induction of Human Embryonic stem cell derived retinal stem cells in vitro using transient overexpression of messenger RNA for BLIMP, ONECUT1 and OTX2, Helen Cifuentes