A collection of master's theses from the Biological Sciences program in the Department of Natural Sciences and Mathematics at Dominican University of California.

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Theses/Capstones from 2016

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Induction of Human Embryonic stem cell derived retinal stem cells in vitro using transient overexpression of messenger RNA for BLIMP, ONECUT1 and OTX2, Helen Cifuentes

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Inhibition of MCF-7 Breast Cancer Cell Proliferation by Diarylthiourea Analogs, Maryam Fallatah

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Synaptic Homeostasis at the Drosophila Neuromuscular Junction: Molecular Mechanisms and Developmental Adaptation, Lindsay A. Gray

Exploring the Role of Oxytocin Signaling in Aging Using Caenorhabditis elegans, Kandyce M. Hamilton

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Integrity of the Barrier Epithelium in Drosophila Gut is Mediated by Factors That Regulate Intestinal Stem Cell Activity, Adam A. Kinion

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Rac1 and IRE1 are Required to Prevent Early Loss of Intestinal Homeostasis in Drosophila melanogaster, Mauricio M. Ortega

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Modeling Therapeutic Strategies for Diabetic Pathologies, Alexander Rifkind

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Evaluation of Seizure Threshold as an Early Behavioral Marker of Disease Progression in the Mouse Model of Mucopolysaccharidosis IIIA, Pamela Santiago

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Targeting Estrogen Receptor Negative Breast Cancer Cells Using Diarylthiourea Analogs of SHetA2, Hongye Zou

Theses/Capstones from 2015

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Investigating Potential Therapies to Decrease the Rate of Cystine Stone Growth in Slc3a1-/- Mice, Sruthi Damodar

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Investigation of Dual Stage Acridones as a Potent Malaria Treatment, Stephanie Huezo

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Modeling Uric Acid Kidney Stones Disease in D. melanogaster using RNAi and Dietary Modulation, Hai T.H. Lu

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Proteins Involved in HDACi Induced Decay of ERBB2 Transcripts in Breast Cancer, Sadaf Malik

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Ectodomain Mutations Alter the Proteolysis of the Amyloid-β Precursor Protein (APP), Michael S. Mitsumori

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Efficient In Vitro Development of Photoreceptors from Human Pluripotent Stem Cells, Joseph C. Reynolds

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Development of Quantitative Tools for the Characterization and Analysis of the Blood Brain Barrier in Normal and MPS IIIB Mice, Sara M. Rigney

Theses/Capstones from 2014

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Neural Stem Cells as a Model to Study Huntington’s Disease, Rawan Bakhsh

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Evaluation of Select Publicly Available in Silico Methods for Predicting Functional Effects of Missense Mutations in the GALNS Gene, Kathryn Davidson

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MicroRNA Expression Signature of Retinal Pigmented Epithelial Cells Associated with the Phenotype of Age-Related Macular Degeneration, Mark Anthony Gutierrez

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Consequences of Endogenous Mitochondrial Oxidative Stress in the Heart, Kristin Alisha Koenig

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Application of High-Performance Liquid-Chromatography Mass-Spectrometry Platform to Study Metabolism and Epigenetic Control of Metabolism, Kylie Patricia Mitchell

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Effects of Heregulin on Muscle: A Biochemical and Histological Analysis, Nicole Justine Moss

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Alendronate Alters Single Cell Gene Expression of Cortical Osteoblast Lineage Cells During Bone Loss, Ryan Jakob Murphy

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Apolipoprotein E4 and SirT1 Interaction in Alzheimer’s Disease, Brittany Ann Philpot

Theses/Capstones from 2013

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Investigation of the Role of TOR and Nutrient Restriction on Lifespan of Arabidopsis thaliana, Debashree Banerjee