Theses/Capstones from 2024
The Impact of Mutant Protein Disulfide Isomerase A3 and p21-Positive Cell Clearance on Cognitive Function in Mouse Models, Harrison Baker
Advanced Spatial Analysis of Neural Targets Using Light Sheet Fluorescence Microscopy and Spatial Proteomics, Joshua Brindley
Investigating the mechanism of action of a highly potent haloalkoxyacridone against Plasmodium falciparum, Jordan Charlton
New Breast Cancer Drugs Mediate Epigenetic Silencing of ERBB2 via the RNA Exosome, Ana M. Escalante
Exploring the Role of Mitochondrial Fission Factor (MFF) in Murine Reproduction, Wendy Jara
Deciphering the Complex Networks of Aging Through a Glycation Lowering Tool and the Effects of Methylglyoxal (MGO) on Adipocytes, Edgard Morazan
Formation of Environmentally Persistent Free Radicals on the Surface of Iron Oxide and Interior of Montmorillonite Clay, Reuben Oumnov
Investigating the Role of Glycation Stress on Muscle Function and Quality in Aged Mice, Karishma Kamlesh Patel
Screening effectiveness of compounds for delay of Alzheimer’s Disease pathogenesis in Caenorhabditis elegans and mammalian cell culture, Brielle Rapsas
Advancing Translational Research in Neurodevelopmental Disorders using a Human Neuronal Xenograft (HuNeuX) Model, Lizet Reyes Rodas
Theses/Capstones from 2023
Identification and Characterization of Novel Senescent Cell Biomarker and Age-Dependent Functional Decline Innate Immune Cells in Mice, Ashley Brauning
Investigating the therapeutic effect of glycation-lowering compounds on murine models of menopause-induced Alzheimer's Disease, Lizbeth Enriquez Najera
Comprehensive investigation of the role of CD38 in ovarian NAD+ metabolism and reproductive aging, Lauren Haky
An Investigation of The Dominant-Negative Effect of Multiple HAE Type I, SERPING1 Mutations Through In Vitro Model(s), Nicole Hernandez
Detection and Capture of Nitrogen Fixing Bacteria From Soil and Roots Using Plant Specific Lectins, Alana Horton
A Mechanistic Evaluation of Naturally Occurring IGF1R 3’UTR Gene Variants Altering Disease Outcomes in Women, Theron Niel
Theses/Capstones from 2022
Small Molecule Compound with Indole Moiety Protects Against Alzheimer’s Disease Pathology in C. elegans and Mammalian Cell Culture Models, Elena Battistoni
Exploring the Diet Dependent Role of Oxidation Resistance 1 in regulating Retromer function, Enrique Carrera
Techniques to Analyze the Pathophysiology of Aging from Induced Senescence and SOD2 loss, Asia Davis-Castillo
Investigating Transcriptomic and Embryonic Differences Between Cave and Surface Populations of Asellus aquaticus, Haeli Lomheim
Uncovering the Role of Progranulin in Ameliorating Lysosomal Storage Disease, Angelina Malagodi
Unraveling the Pathways Involved in Intestinal Repair After Ionizing Radiation Damage, Blaine Pattavina
Exploring Glycolysis-Mediated Metabolic Stress and Mitigation Strategies in the CNS Through Glycation-Lowering Therapy, Cavan Patterson
Characterizing the Natural History of Liver Pathology in the Alpha 1 Antitrypsin Deficiency Mouse Model, Selma Takajjart