All Conference Presentations, Performances and Exhibits
Huntington's Disease and Stem Cells
Location
Guzman 114
Start Date
4-15-2016 2:35 PM
End Date
4-15-2016 3:00 PM
Student Type
Undergraduate - Honors
Faculty Mentor(s)
Kiowa Bower, Ph.D.
Presentation Format
Oral Presentation
Abstract/Description
Huntington's Disease (HD) is a progressive neurodegenerative disease with significant psychiatric and physical effects. We first began by implementing cell passaging procedures with both embryonic stem cells (ESCs) and neural stem cells (NSCs). Further, my thesis includes a synopsis of prior research to date regarding the overview of HD and epidemiology. Finally, in this study we use neural stem cells (NSCs) as a model of HD. The Huntingtin in one cell lines contains 140 glutamine repeats (140Q) while the “wildtype” control cells are 7Q. Our results conclude the difference between a healthy and HD-affected NSC.
Huntington's Disease and Stem Cells
Guzman 114
Huntington's Disease (HD) is a progressive neurodegenerative disease with significant psychiatric and physical effects. We first began by implementing cell passaging procedures with both embryonic stem cells (ESCs) and neural stem cells (NSCs). Further, my thesis includes a synopsis of prior research to date regarding the overview of HD and epidemiology. Finally, in this study we use neural stem cells (NSCs) as a model of HD. The Huntingtin in one cell lines contains 140 glutamine repeats (140Q) while the “wildtype” control cells are 7Q. Our results conclude the difference between a healthy and HD-affected NSC.
Comments
I worked with Matthew Erbst in this research so while similar, he focused more on the molecular aspect within a chapter.