A collection of faculty scholarship from the Department of Natural Sciences and Mathematics at Dominican University of California

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Submissions from 2021

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The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to, James M. Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F. Gnädig, Charisse Flerida A. Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Ric N. Price, Grennady Wirjanata, Rintis Noviyanti, Patrick Tumwebaze, Roland A. Cooper, Philip J. Rosenthal, Laura M. Sanz, Francisco-Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C. Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A. Fidock, and Didier Leroy

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The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to, James M. Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F. Gnädig, Charisse Flerida A. Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Ric N. Price, Grennady Wirjanata, Rintis Noviyanti, Patrick K. Tumwebaze, Roland A. Cooper, Philip J. Rosenthal, Laura M. Sanz, Francisco-Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C. Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A. Fidock, and Didier Leroy

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Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series., Michael J. Palmer, Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey Gerasyuto, Sreekanth Kokkonda, Farah El Mazouni, John White, Karen L White, Josefine Striepen, Jade Bath, Kyra A. Schindler, Tomas Yeo, David M. Shackleford, Sachel Mok, Ioanna Deni, Aloysus Lawong, Ann Huang, Gong Chen, Wen Wang, Jaya Jayaseelan, Kasiram Katneni, Rahul Patil, Jessica Saunders, Shatrughan P. Shahi, Rajesh Chittimalla, Iñigo Angulo-Barturen, María Belén Jiménez-Díaz, Sergio Wittlin, Patrick K. Tumwebaze, Philip J. Rosenthal, Roland A. Cooper, Anna Caroline Campos Aguiar, Rafael V C Guido, Dhelio B. Pereira, Nimisha Mittal, Elizabeth A Winzeler, Diana R. Tomchick, Benoît Laleu, Jeremy N. Burrows, Pradipsinh K Rathod, David A. Fidock, Susan A. Charman, and Margaret A. Phillips

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Use of Foliar Chemical Treatments to Induce Disease Resistance in Rhododendrons Inoculated with Phytophthora ramorum, Craig Ramsey, Paul C. Freebury, Debra H. Newman, Wolfgang Schweigkofler, Leland J. Cseke, and Steven E. Newman

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Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study, Patrick K. Tumwebaze, Thomas Katairo, Martin Okitwi, Oswald Byaruhanga, Stephen Orena, Victor Asua, Marvin Duvalsaint, Jennifer Legac, Sevil Chelebieva, Frida G. Ceja, Stephanie A. Rasmussen, Melissa D. Conrad, Samuel L. Nsobya, Ozkan Aydemir, Jeffrey A. Bailey, Brett R. Bayles, Philip J. Rosenthal, and Roland A. Cooper

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Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice., Wenhu Zhan, Hao Zhang, John Ginn, Annie Leung, Yi J. Liu, Mayako Michino, Akinori Toita, Rei Okamoto, Tzu-Tshin Wong, Toshihiro Imaeda, Ryoma Hara, Takafumi Yukawa, Sevil Chelebieva, Patrick K. Tumwebaze, Maria Jose Lafuente-Monasterio, Maria Santos Martinez-Martinez, Jeremie Vendome, Thijs Beuming, Kenjiro Sato, Kazuyoshi Aso, Philip J. Rosenthal, Roland A. Cooper, Peter T Meinke, Carl F. Nathan, Laura A. Kirkman, and Gang Lin

Submissions from 2020

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Impact of the First COVID-19 Shelter-in-place Order in the United States on Emergency Department Utilization, Marin County, California, Brett R. Bayles, Michaela George, Haylea Hannah, Patti L. Culross, Rochelle Ereman, Dustin W. Ballard, and Matthew Willis

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Spatiotemporal dynamics of vector-borne disease risk across human land-use gradients: examining the role of agriculture, indigenous territories, and protected areas in Costa Rica, Brett R. Bayles, Andria Rusk, Rebecca Christofferson, Gabriellah Agar, Maria Alvarez Pineda, Bobin Chen, Kiera Dagy, Emma Kelly, Tyler Hummel, Kira Kuwada, Serena Martin, Alec Murrer, and Carlos Faerron Guzmán

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Spatiotemporal trends of cutaneous leishmaniasis in Costa Rica., Brett R. Bayles, Andria E Rusk, Maria Alvarez Pineda, Bobin Chen, Keira Lee Dagy, Tyler Hummel, Kira Kuwada, Serena Martin, and Carlos Faerron Guzmán

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Prevalence of Batrachochytrium dendrobatidis in immature eastern hellbenders Cryptobranchus alleganiensis from North Carolina, USA., Lauren Diaz, Obed Hernandez-Gomez, Shem D Unger, Lori A Williams, and Catherine M Bodinof Jachowski

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Climate change disturbs wildlife microbiomes, Obed Hernandez-Gomez

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Invasive vegetation affects amphibian skin microbiota and body condition, Obed Hernandez-Gomez, Allison Q. Byrne, Alex R. Gunderson, Thomas S. Jenkinson, Clay F. Noss, Andrew P. Rothstein, Molly C. Womack, and Erica B. Rosenblum

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Amphibian Host and Skin Microbiota Response to a Common Agricultural Antimicrobial and Internal Parasite, Obed Hernandez-Gomez, Vanessa Wuerthner, and Jessica Hua

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Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials., Papireddy Kancharla, Rozalia A. Dodean, Yuexin Li, Sovitj Pou, Brandon Pybus, Victor Melendez, Lisa Read, Charles E Bane, Brian Vesely, Mara Kreishman-Deitrick, Chad Black, Qigui Li, Richard J. Sciotti, Raul Olmeda, Thu-Lan Luong, Heather Gaona, Brittney Potter, Jason Sousa, Sean Marcsisin, Diana Caridha, Lisa Xie, Chau Vuong, Qiang Zeng, Jing Zhang, Ping Zhang, Hsiuling Lin, Kirk Butler, Norma Roncal, Lacy Gaynor-Ohnstad, Susan E. Leed, Christina Nolan, Frida G. Ceja, Stephanie A. Rasmussen, Patrick K. Tumwebaze, Philip J. Rosenthal, Jianbing Mu, Brett R. Bayles, Roland A. Cooper, Kevin A. Reynolds, Martin J. Smilkstein, Michael K. Riscoe, and Jane X. Kelly

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A novel bioaugmentation technique effectively increases the skin-associated microbial diversity of captive eastern hellbenders, Erin K. Kenison, Obed Hernandez-Gomez, and Rod N. Williams

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Sources and Toxicity of Mercury in the San Francisco Bay Area, Spanning California and Beyond., Mietek Kolipinski, Mani Subramanian, Kristina Kristen, Steven Borish, and Stacy Ditta

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Comment on “Amphibian fungal panzootic causes catastrophic and ongoing loss of biodiversity”, Max R. Lambert, Molly C. Womack, Allison Q. Byrne, Obed Hernandez-Gomez, Clay F. Noss, Andrew P. Rothstein, Davis C. Blackburn, James P. Collins, Martha L. Crump, Michelle S. Koo, Priya Nanjappa, Louise Rollins-Smith, Vance T. Vrendenburg, and Erica B. Rosenblum

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Field Evaluation of a Novel, Granular Soil Fumigant for Controlling Phytophthora ramorum in Field Nursery Soils, Marissa L. Layman, Craig Ramsey, Wolfgang Schweigkofler, and Steven E. Newman

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Total Cellular ATP Production Changes With Primary Substrate in MCF7 Breast Cancer Cells., Maggie Louie, Justin Ton, Maurice L. Brady, Diem T. Le, Jordon N. Mar, Chad A Lerner, Akos A Gerencser, and Shona A. Mookerjee

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Rapid Recovery and Detection of Phytophthora ramorum Propagules in Nursery Water, Douglas Luster, Karen Suslow, Supriya Sharma, Wolfgang Schweigkofler, and Vernon Huffman

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Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation., Kirthana M. V. Sindhe, Wesley Wu, Jenny Legac, Yong-Kang Zhang, Eric E. Easom, Roland A. Cooper, Jacob J. Plattner, Yvonne R. Freund, Joseph L. DeRisi, and Philip J. Rosenthal

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Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation., Kirthana M. V. Sindhe, Wesley Wu, Jenny Legac, Yong-Kang Zhang, Eric E. Easom, Roland A. Cooper, Jacob J. Plattner, Yvonne R. Freund, Joseph L. DeRisi, and Philip J. Rosenthal

Submissions from 2019

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Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα., Mathew Bloomfield and Maggie Louie

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Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials., Rozalia A. Dodean, Papireddy Kancharla, Yuexin Li, Victor Melendez, Lisa Read, Charles E. Bane, Brian Vesely, Mara Kreishman-Deitrick, Chad Black, Qigui Li, Richard J. Sciotti, Raul Olmeda, Thu-Lan Luong, Heather Gaona, Brittney Potter, Jason Sousa, Sean Marcsisin, Diana Caridha, Lisa Xie, Chau Vuong, Qiang Zeng, Jing Zhang, Ping Zhang, Hsiuling Lin, Kirk Butler, Norma Roncal, Lacy Gaynor-Ohnstad, Susan E. Leed, Christina Nolan, Stephanie J. Huezo, Stephanie A. Rasmussen, Melissa T. Stephens, John C. Tan, Roland A. Cooper, Martin J. Smilkstein, Sovitj Pou, Rolf W. Winter, Michael K. Riscoe, and Jane X. Kelly

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Developmental Transcriptomic Analysis of the Cave-Dwelling Crustacean, Asellus aquaticus, Joshua B. Gross, Dennis A. Sun, Brian M. Carlson, Sivan Brodo-Abo, and Meredith E. Protas