A collection of faculty scholarship from the Department of Natural Sciences and Mathematics at Dominican University of California

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Submissions from 2024

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NewFeaturesofLaboratory-GeneratedEPFRsfrom1,2-Dichlorobenzene(DCB)and2‑Monochlorophenol(MCP), Lavrent Khachatryan, Marwan Y. Rezk, Divine Nde, Farhana Hasan, Slawomir Lomnicki, Dorin Boldor, Robert Cook, Phillip Sprunger, Randall W. Hall, and Stephania Cormier

Submissions from 2023

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Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda., Melissa D. Conrad, Victor Asua, Shreeya Garg, David Giesbrecht, Karamoko Niaré, Sawyer Smith, Jane F Namuganga, Thomas Katairo, Jennifer Legac, Rebecca M. Crudale, Patrick K. Tumwebaze, Samuel L. Nsobya, Roland A. Cooper, Moses R. Kamya, Grant Dorsey, Jeffrey A. Bailey, and Philip J. Rosenthal

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Wicked Problems and the Invention of Calculus, Ernesto Diaz

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From the organismal to biosphere levels: environmental impacts on the amphibian microbiota, Obed Hernandez-Gomez and Jessica Hua

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Wildfires Disturb the Natural Skin Microbiota of Terrestrial Salamanders, Lubna Mulla and Obed Hernandez-Gomez

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First report of Phytophthora ramorum on Cotoneaster sp. in the USA., Tomas Pastalka, Nilwala Abeysekara, and Wolfgang Schweigkofler

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Standing genetic variation as a potential mechanism of novel cave phenotype evolution in the freshwater isopod, Asellus aquaticus, Lizet R. Rodas, Serban M. Sarbu, Raluca Bancila, Devon Price, Žiga Fišer, and Meredith E. Protas

Submissions from 2022

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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183., Laura E. de Vries, Patrick A M Jansen, Catalina Barcelo, Justin Munro, Julie M J Verhoef, Charisse Flerida A Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M Bolscher, Claudia Demarta-Gatsi, Rob W M Henderson, Tonnie Huijs, Karin M J Koolen, Patrick K Tumwebaze, Tomas Yeo, Anna C C Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V C Guido, María Belén Jiménez-Diaz, Dhelio B Pereira, Rosemary Rochford, Camille Roesch, Laura M Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W Sauerwein, Joost Schalkwijk, Pedro H H Hermkens, Roger V Bonnert, Brice Campo, David A Fidock, Manuel Llinás, Jacquin C Niles, Taco W A Kooij, and Koen J Dechering

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Re-evaluation of the Fijianolide/Laulimalide Chemotype Suggests an Alternate Mechanism of Action for C-15/C-20 Analogs., Joseph D Morris, Leila Takahashi-Ruiz, Lauren N Persi, Jonathan C Summers, Erin P McCauley, Peter Y W Chan, Gabriella Amberchan, Itzel Lizama-Chamu, David A Coppage, Phillip Crews, April L Risinger, and Tyler A. Johnson

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Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria., Benjamin R Taft, Fumiaki Yokokawa, Tom Kirrane, Anne-Catherine Mata, Richard Huang, Nicole Blaquiere, Grace Waldron, Bin Zou, Oliver Simon, Subramanyam Vankadara, Wai Ling Chan, Mei Ding, Sandra Sim, Judith Straimer, Armand Guiguemde, Suresh B Lakshminarayana, Jay Prakash Jain, Christophe Bodenreider, Christopher Thompson, Christian Lanshoeft, Wei Shu, Eric Fang, Jafri Qumber, Katherine Chan, Luying Pei, Yen-Liang Chen, Hanna Schulz, Jessie Lim, Siti Nurdiana Abas, Xiaoman Ang, Yugang Liu, Iñigo Angulo-Barturen, María Belén Jiménez-Díaz, Francisco Javier Gamo, Benigno Crespo-Fernandez, Philip J Rosenthal, Roland A. Cooper, Patrick Tumwebaze, Anna Caroline Campos Aguiar, Brice Campo, Simon Campbell, Jürgen Wagner, Thierry T Diagana, and Christopher Sarko

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In Vivo Evaluation of (-)-Zampanolide Demonstrates Potent and Persistent Antitumor Efficacy When Targeted to the Tumor Site., Leila Takahashi-Ruiz, Joseph D Morris, Phillip Crews, Tyler A Johnson, and April L Risinger

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Life Stage and Proximity to Roads Shape the Skin Microbiota of Eastern Newts (Notophthalmus viridescens), Vanessa P. Wuerthner, Jessica Hua, and Obed Hernandez-Gomez

Submissions from 2021

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Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda., Victor Asua, Melissa D. Conrad, Ozkan Aydemir, Marvin Duvalsaint, Jennifer Legac, Elias Duarte, Patrick Tumwebaze, Deborah M Chin, Roland A. Cooper, Adoke Yeka, Moses R Kamya, Grant Dorsey, Sam L Nsobya, Jeffrey Bailey, and Philip J Rosenthal

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Skin bacterial metacommunities of San Francisco Bay Area salamanders are structured by host genus and habitat quality., Shannon Buttimer, Obed Hernandez-Gomez, and Erica Bree Rosenblum

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Can repurposing drugs play a role in malaria control?, Roland A. Cooper and Laura Kirkman

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Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum., Marvin Duvalsaint, Melissa D. Conrad, Stephen Tukwasibwe, Patrick K Tumwebaze, Jennifer Legac, Roland A. Cooper, and Philip J Rosenthal

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Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum Isolates., Oriana Kreutzfeld, Stephanie A Rasmussen, Aarti A. Ramanathan, Patrick K Tumwebaze, Oswald Byaruhanga, Thomas Katairo, Victor Asua, Martin Okitwi, Stephen Orena, Jennifer Legac, Melissa D Conrad, Samuel L Nsobya, Ozkan Aydemir, Jeffrey Bailey, Maelle Duffey, Brett R. Bayles, Akhil B Vaidya, Roland A. Cooper, and Philip J Rosenthal

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The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to, James M. Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F. Gnädig, Charisse Flerida A. Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Ric N. Price, Grennady Wirjanata, Rintis Noviyanti, Patrick Tumwebaze, Roland A. Cooper, Philip J Rosenthal, Laura M Sanz, Francisco Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A Fidock, and Didier Leroy

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The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to, James M. Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F Gnädig, Charisse Flerida A Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Ric N. Price, Grennady Wirjanata, Rintis Noviyanti, Patrick Tumwebaze, Roland A. Cooper, Philip J. Rosenthal, Laura M. Sanz, Francisco Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C. Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A Fidock, and Didier Leroy

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Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series., Michael J. Palmer, Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey Gerasyuto, Sreekanth Kokkonda, Farah El Mazouni, John White, Karen L White, Josefine Striepen, Jade Bath, Kyra A. Schindler, Tomas Yeo, David M. Shackleford, Sachel Mok, Ioanna Deni, Aloysus Lawong, Ann Huang, Gong Chen, Wen Wang, Jaya Jayaseelan, Kasiram Katneni, Rahul Patil, Jessica Saunders, Shatrughan P. Shahi, Rajesh Chittimalla, Iñigo Angulo-Barturen, María Belén Jiménez-Díaz, Sergio Wittlin, Patrick K. Tumwebaze, Philip J. Rosenthal, Roland A. Cooper, Anna Caroline Campos Aguiar, Rafael V C Guido, Dhelio B. Pereira, Nimisha Mittal, Elizabeth A Winzeler, Diana R. Tomchick, Benoît Laleu, Jeremy N. Burrows, Pradipsinh K Rathod, David A Fidock, Susan A. Charman, and Margaret A. Phillips

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Use of Foliar Chemical Treatments to Induce Disease Resistance in Rhododendrons Inoculated with Phytophthora ramorum, Craig Ramsey, Paul C. Freebury, Debra H. Newman, Wolfgang Schweigkofler, Leland J. Cseke, and Steven E. Newman

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Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study, Patrick K. Tumwebaze, Thomas Katairo, Martin Okitwi, Oswald Byaruhanga, Stephen Orena, Victor Asua, Marvin Duvalsaint, Jennifer Legac, Sevil Chelebieva, Frida G Ceja, Stephanie A Rasmussen, Melissa D Conrad, Samuel L. Nsobya, Ozkan Aydemir, Jeffrey A Bailey, Brett R. Bayles, Philip J Rosenthal, and Roland A. Cooper

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Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice., Wenhu Zhan, Hao Zhang, John Ginn, Annie Leung, Yi J. Liu, Mayako Michino, Akinori Toita, Rei Okamoto, Tzu-Tshin Wong, Toshihiro Imaeda, Ryoma Hara, Takafumi Yukawa, Sevil Chelebieva, Patrick K Tumwebaze, Maria Jose Lafuente-Monasterio, Maria Santos Martinez-Martinez, Jeremie Vendome, Thijs Beuming, Kenjiro Sato, Kazuyoshi Aso, Philip J Rosenthal, Roland A. Cooper, Peter T Meinke, Carl F. Nathan, Laura A. Kirkman, and Gang Lin

Submissions from 2020

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Prevalence of Batrachochytrium dendrobatidis in immature eastern hellbenders Cryptobranchus alleganiensis from North Carolina, USA., Lauren Diaz, Obed Hernandez-Gomez, Shem D Unger, Lori A Williams, and Catherine M Bodinof Jachowski

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Climate change disturbs wildlife microbiomes, Obed Hernandez-Gomez