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Theses/Capstones from 2019

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The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research., James B McAlpine, Shao-Nong Chen, Andrei Kutateladze, John B MacMillan, Giovanni Appendino, Andersson Barison, Mehdi A Beniddir, Maique W Biavatti, Stefan Bluml, Asmaa Boufridi, Mark S Butler, Robert J Capon, Young H Choi, David Coppage, Phillip Crews, Michael T Crimmins, Marie Csete, Pradeep Dewapriya, Joseph M Egan, Mary J Garson, Grégory Genta-Jouve, William H Gerwick, Harald Gross, Mary Kay Harper, Precilia Hermanto, James M Hook, Luke Hunter, Damien Jeannerat, Nai-Yun Ji, Tyler A. Johnson, David G I Kingston, Hiroyuki Koshino, Hsiau-Wei Lee, Guy Lewin, Jie Li, Roger G Linington, Miaomiao Liu, Kerry L McPhail, Tadeusz F Molinski, Bradley S Moore, Joo-Won Nam, Ram P Neupane, Matthias Niemitz, Jean-Marc Nuzillard, Nicholas H Oberlies, Fernanda M M Ocampos, Guohui Pan, Ronald J Quinn, D Sai Reddy, Jean-Hugues Renault, José Rivera-Chávez, Wolfgang Robien, Carla M Saunders, Thomas J Schmidt, Christoph Seger, Ben Shen, Christoph Steinbeck, Hermann Stuppner, Sonja Sturm, Orazio Taglialatela-Scafati, Dean J Tantillo, Robert Verpoorte, Bin-Gui Wang, Craig M Williams, Philip G Williams, Julien Wist, Jian-Min Yue, Chen Zhang, Zhengren Xu, Charlotte Simmler, David C Lankin, Jonathan Bisson, and Guido F Pauli

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Novel flexible heteroarotinoid, SL-1-39, inhibits HER2-positive breast cancer cell proliferation by promoting lysosomal degradation of HER2., Hongye Zou, Mary B. Sevigny, Shengquan Liu, David T. Madden, and Maggie Louie

Theses/Capstones from 2018

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The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells., Nicholas Lorig-Roach, Frances Hamkins-Indik, Tyler A. Johnson, Karen Tenney, Frederick A Valeriote, and Phillip Crews

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Embryonic origin and genetic basis of cave associated phenotypes in the isopod crustacean Asellus aquaticus., Hafasa Mojaddidi, Franco E Fernandez, Priscilla A Erickson, and Meredith E. Protas

Theses/Capstones from 2017

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A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine, Satish K. Dhingra, Devasha Redhi, Jill M. Combrinck, Tomas Yeo, John Okombo, Philipp P. Henrich, Ann N. Cowell, Purva Gupta, Matthew L. Stegman, Jonathan M. Hoke, Roland A. Cooper, Elizabeth Winzeler, Sachel Mok, Timothy J. Egan, and David A. Fidock

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Identification of the First Marine-Derived Opioid Receptor "Balanced" Agonist with a Signaling Profile That Resembles the Endorphins., Tyler A. Johnson, Laura Milan-Lobo, Tao Che, Madeline Ferwerda, Eptisam Lambu, Nicole L McIntosh, Fei Li, Li He, Nicholas Lorig-Roach, Phillip Crews, and Jennifer L Whistler

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Another Look at Pyrroloiminoquinone Alkaloids-Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic Analogues., Sheng Lin, Erin P McCauley, Nicholas Lorig-Roach, Karen Tenney, Cassandra N Naphen, Ai-Mei Yang, Tyler A. Johnson, Thalia Hernadez, Ramandeep Rattan, Frederick A Valeriote, and Phillip Crews

Theses/Capstones from 2016

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Opsin Repertoire and Expression Patterns in Horseshoe Crabs: Evidence from the Genome of Limulus polyphemus (Arthropoda: Chelicerata), Barbara-Anne Battelle, Joseph F. Ryan, Karen E. Kempler, Spencer R. Saraf, Catherine E. Marten, Wesley C. Warren, Patrick J. Minx, Michael J. Montague, Pamela J. Green, Skye A. Schmidt, Lucinda Fulton, Nipam H. Patel, Meredith E. Protas, Richard K. Wilson, and Megan L. Porter

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Sign Learning Kink-based (SiLK) Quantum Monte Carlo for Molecular Systems, Xiaoyao Ma, Randall W. Hall, Frank Loffler, Karol Kowalski, Kiran Bhaskaran-Nair, Mark Jarrell, and Juana Moreno

Theses/Capstones from 2015

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Antibacterial activity of native California medicinal plant extracts isolated from Rhamnus californica and Umbellularia californica., Maria G. Carranza, Mary B. Sevigny, Debashree Banerjee, and Lacie Fox-Cubley

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Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based on Parasitological and Molecular Assays, Roland A. Cooper, Melissa D. Conrad, Quentin D. Watson, Stephanie J. Huezo, Harriet Ninsiima, Patrick Tumwebaze, Samuel L. Nsobya, and Philip J. Rosenthal

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Lack of resistance of Plasmodium falciparum to dihydroartemisinin in Uganda based on parasitogolgical and molecular assays, Roland A. Cooper, Melissa D. Conrad, Quentin D. Watson, Stephanie J. Huezo, Harriet Ninsiima, Patrick Tumwebaze, Samuel L. Nsobya, and Philip J. Rosenthal

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The Sign Learning Kink (SiLK) based Quantum Monte Carlo for Molecular Systems, Xiaoyao Ma, Frank Loffler, Randall Hall, Karol kowalski, Mark Jarrell, and Juana Moreno

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Acute and chronic cadmium exposure promotes E-cadherin degradation in MCF7 breast cancer cells., Esmeralda Ponce, Maggie Louie, and Mary B. Sevigny

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Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities, Serena Pulcini, Henry M. Staines, Andrew H. Lee, Sarah H. Shafik, Guillaume Bouyer, Catherine M. Moore, Daniel A. Daley, Matthew J. Hoke, Lindsey M. Altenhofen, Heather J. Painter, Jianbing Mu, David J. P. Ferguson, Manuel Llinas, Rowen E. Martin, David A. Fidock, Roland Cooper, and Sanjeev Krishna

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Resistance Inducers and Plant Growth Regulators Show only Limited and Transient Effects on Infection Rates, Growth Rates and Symptom Expression of Apple Trees Infected with ‘Candidatus Phytoplasma mali’, Silva Schmidt, Sanja Baric, Maya Massenz, Thomas Letschka, Valerie Vanas, Manfred Wolf, Christine Kerschbamer, Roland Zelger, and Wolfgang Schweigkofler

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A Transcriptomic Analysis of Cave, Surface, and Hybrid Isopod Crustaceans of the Species Asellus aquaticus, Bethany A. Stahl, Joshua B. Gross, Daniel I. Speiser, Todd H. Oakley, Nipham H. Patel, Douglas B. Gould, and Meredith E. Protas

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Biosynthetic products from a nearshore-derived gram-negative bacterium enable reassessment of the kailuin depsipeptides., Christine M. Theodore, Nicholas Lorig-Roach, Patrick C Still, Tyler A. Johnson, Marija Drašković, Joshua A Schwochert, Cassandra N Naphen, Mitchell S Crews, Simone A Barker, Frederick A Valeriote, R Scott Lokey, and Phillip Crews

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Impact of Antimalarial Treatment and Chemoprevention on the Drug Sensitivity of Malaria Parasites Isolated from Ugandan Children, Patrick Tumwebaze, Melissa D. Conrad, Andrew Walakira, Norbert LeClair, Oswald Byaruhanga, Christine Nakazibwe, Benjamin Kozak, Jessica Bloome, Jaffer Okiring, Abel Kakuru, Victor Bigira, James Kapisi, Jennifer Legac, Jiri Gut, Roland A. Cooper, Moses R. Kamya, Diane V. Havlir, Grant Dorsey, Bryan Greenhouse, Samuel L. Nsobya, and Philip J. Rosenthal

Theses/Capstones from 2014

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Environmentally Persistent Free Radicals (EPFRs). 3. Free versus Bound Hydroxyl Radicals in EPFR Aqueous Solutions, Lavrent Khachatryan, Cheri A. McFerrin, Randall W. Hall, and Barry Dellinger

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Perceived Benefits and Challenges of Interprofessional Education Based on a Multidisciplinary Faculty Member Survey, David Benjamin Lash, Mitchell J. Barnett, Nirali Parekh, Anita Shieh, Maggie Louie, and Terrill T-L. Tang

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Steaming Inactivates Phytophthora ramorum, Causal Agent of Sudden Oak Death and Ramorum Blight, from Infested Nursery Soils in California, Wolfgang Schweigkofler, Kathleen Kosta, Vernon Huffman, Supriya Sharma, Karen Suslow, and Sibdas Ghosh

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Using phylogenetically-informed annotation (PIA) to search for light-interacting genes in transcriptomes from non-model organisms, Daniel I. Speiser, M. Sabrina Pankey, Alexander K. Zaharoff, Barbara A. Battelle, Heather D. Bracken-Grissom, Jesse W. Breinholt, Seth M. Bybee, Thomas W. Cronin, Anders Garm, Annie R. Lindgren, Nipam H. Patel, Megan L. Porter, Meredith E. Protas, Anja S. Rivera, Jeanne M. Serb, Kirk S. Zigler, Keith A. Crandall, and Todd H. Oakley

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Scrutinizing the scaffolds of marine biosynthetics from different source organisms: Gram-negative cultured bacterial products enter center stage., Patrick C Still, Tyler A Johnson, Christine M Theodore, Steven T Loveridge, and Phillip Crews

Theses/Capstones from 2013

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Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders., Tyler A. Johnson, Johann Sohn, Wayne D Inman, Leonard F Bjeldanes, and Keith Rayburn