Graduation Date
5-2019
Document Type
Culminating Project
Degree Name
Master of Science
Program
Clinical Laboratory Sciences
Program Director
Mary B. Sevigny, PhD
Faculty Advisor
Howard Koo
Project Supervisor
James Lapan
Abstract
Matrix-Assisted Laser Desorption and Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has been revealed as an invaluable platform for identifying anaerobic bacteria in the clinical laboratory over traditional methods such as the RapID ANA II System.
A qualitative comparison is made, through the analysis of methodologies and specifications, to determine whether the RapID ANA II system or Bruker MALDI-TOF MS is more suitable for identifying anaerobic organism in the clinical laboratory. Based on the data reviewed, the MALDI-TOF MS is a more intuitive platform within the clinical laboratory due to its increased specificity, cost-effectiveness, and shorten turnaround time for the identification of anaerobes.
Included in
Laboratory and Basic Science Research Commons, Medical Microbiology Commons, Medical Molecular Biology Commons