Document Type

Article

Source

Journal of Intellectual Disability Research

ISSN

1365-2788

Volume

53

Issue

1

First Page

11

Last Page

18

Publication Date

1-2009

Department

Occupational Therapy

Abstract

Background—Previous studies suggested that children diagnosed with Fragile X Syndrome (FXS) often meet criteria for autism or PDD. This study describes the fine motor abilities of children diagnosed with FXS with and without autism spectrum disorder, and compares the motor scores of those groups controlling for cognitive level.

Method—Forty-eight children, ages 12-76 months (SD=16) diagnosed with FXS were assessed with the Mullen Scales of Early Learning, and the Autism Diagnostic Observation Schedule (ADOS). Their parents were interviewed with the Autism Diagnostic Interview-Revised (ADI-R). We used a one-way analysis of variance (ANOVA) to determine if the fine motor scale of the Mullen would show group differences based on autism classifications for the sample. In addition, we used Pearson correlation coefficient to examine the relationship between the cognitive level, the autism severity and the motor abilities. Lastly, we conducted a one-way analysis of covariance (ANCOVA) to determine the difference between the motor abilities of the ASD groups controlling for cognitive level

Results—We found that 60% of the children with FXS met criteria for autism or PDD-NOS. Children with FXS with autism and PDD-NOS had lower fine motor scores than those without. However, there was no significant association between degree of motor impairment and communication and social impairments after controlling for cognitive level, indicating that cognitive level contributes to impaired motor abilities of children diagnosed with FXS and autism, more than the severity of autism symptoms.

Conclusion—children with FXS and autism are at risk for impaired motor abilities. Implications for development and intervention are discussed.

Rights

Copyright © 2008 The Authors.

PubMed ID

18771512

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