Graduation Year

2025

Document Type

Senior Thesis

Degree

Bachelor of Science in Nursing

Primary Major

Nursing

Primary Minor

Clinical and Counseling Science

Thesis Advisor

Deborah Meshel, BSN, MSN

Abstract

Purpose

The purpose of this study is to compare the safety and long-term effects of topical calcineurin inhibitors (TCIs) and topical corticosteroids (TCS) in pediatric patients diagnosed with atopic dermatitis (AD), and to compare the prescribed treatment use for 6 to 12 months. By providing evidence on prescribed topical treatments, their safety differences, and long-term effects, healthcare professionals can make informed decisions to minimize risks and choose the safest appropriate treatment for children.

Method

This study will employ a quasi-experimental design, and participants aged 2-18 years will be selected from a clinic. Participants and their families will complete an initial baseline survey. Follow-up assessments will be conducted at 1, 3, 6, and 9 months of treatment to evaluate treatment safety and efficacy continuously. Following the intervention, data will be gathered through a final survey and various measurement tools.

Results

If the findings are statistically significant, then it will prove the hypothesis that topical calcineurin inhibitors have fewer long-term effects and are safer to use compared to topical corticosteroids in pediatric patients with atopic dermatitis.

Conclusion

Many children continue to struggle through their early years as parents are hesitant to rely solely on topical steroids due to their numerous risks. The lack of knowledge for parents and families on AD treatment creates a gap for education on alternative therapies such as topical calcineurin inhibitors (TCIs).

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