The Master of Science in Clinical Laboratory Sciences (CLS) with an emphasis in Molecular Diagnostics is a 30-unit, non-thesis program, designed for the practicing Clinical Laboratory Scientist or Medical Laboratory Scientist looking to become a leader in the clinical laboratory. Students who are not already CLS licensed or license-eligible pursue a Master of Science in Molecular Diagnostics.

Students in the CLS program will be prepared to modify systems and procedures in an effort to make the clinical lab more efficient and cost-effective while still emphasizing the importance of obtaining accurate and reproducible patient results. Molecular diagnostic techniques covered by this program include nucleic acid and protein extraction, gel electrophoresis, PCR, fluorescent in situ hybridization (FISH), restriction fragment length polymorphism (RFLP) analysis, and DNA and RNA microarray technology.


Theses/Capstones from 2018


Different Methodologies to Characterize and Diagnose Sickle Cell Disease in Both Developed and Developing Nations, Mohammed AlHarbi

Reducing Turnaround Time of Clinical Laboratory Analysis Through Use of Efficient Blood Collection Techniques, Socorro Buni

Method Verification of Cepheid Xpert Xpress Flu Assay by Polymerase Chain Reaction (PCR), Artemio Dalmaceda


POCT Testing and Importance of Operator Lock-out, Nuha Fadlalla


Determination of the Feasibility of Using Cell-Free DNA (cfDNA) in the Q-Clamp KRAS Codon Specific Mutation Test, Manuel Garcia

Detection and Identification of Gastrointestinal Pathogens in Clinical Samples: Comparison Between two Laboratory Developed Multiplex Real-Time PCR Platforms, Geybi Ariana Garibay

Failure Mode Effects Analysis of Auto-verification in the Clinical Laboratory, Kalev Golubjatnikov


Specimen Accountability Process Change in a Non-Automated Consolidated Microbiology Laboratory, Michael Monh


Implementation Plan to Integrate the Nanosphere Verigene Assay in a High-volume Reference Laboratory and the Anticipated Workflow Benefits to Adopting Rapid Blood Culture Testing, Sofia Nazar

New Clinical Guidelines for Cervical Cancer Screening and the Benefits of Implementing a Primary High-risk Human Papillomavirus Test in a High Volume Reference Laboratory, Dani Rose Ortaleza


Optimization of BRAF V600 Assay as A 2-Step Real-time PCR Protocol, Mimi Phuong


Qualify Microplate Reader’s Specification and Establish the Acceptance Criteria for Modified PicoGreen Kit in Measuring cell-free DNA Concentration in Clinical Laboratory, Huy T. Quach

Validation of TEG5000 Functional Fibrinogen Reagent as Abnormal Quality Control Material for TEG 6s PlateletMapping, Angeli Rose

Instrumentation Acquisition: Do the Numbers Justify the Purchase?, My Tran

Theses/Capstones from 2017

Strategies for Achieving Compliance: Laboratory Developed Software, Christine Aquino

Evaluation and Clinical Implications of Biomarkers of Electronic Cigarette Use, Lee Besana

Implementation and Cost Analysis of Performing Molecular Assays using FFPE Tissue Blocks in the Clinical Laboratory at VA Palo Alto Health Care System, Donna Comandante

Development of a Quality Management System (QMS) in Conformance with International Organization for Standardization (ISO) 13485:2016 Focusing on Sections 4 and 5 by Utilizing Technical Project Management Techniques for CDG Biotech Corporation, Martin Mach

Theses/Capstones from 2016

Implementation of a Clinical Laboratory Science Internship Program at Dominican University of California, Barbara Albonico