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Genetic Variation in Drug Metabolism in Relation to Age, Gender, and Ethnicity

Location

Guzman 114

Start Date

4-15-2016 4:35 PM

End Date

4-15-2016 5:00 PM

Student Type

Undergraduate - Honors

Faculty Mentor(s)

Diara Spain, Ph.D. and Maria Carranza, Ph.D.

Presentation Format

Oral Presentation

Abstract/Description

Drug metabolism is a key part in effectiveness of medications, and more recent studies have gone further into the varying rates and factors involved in drug metabolism in patients. Variability in function has been observed among people of different genders, ages, and ethnic background. My literature review investigates case studies on abnormal breakdown of drugs observed in people sharing certain genetic polymorphisms. This is likely resulting from altered metabolic pathways for the drugs, which can slow down or speed up the breakdown of the active compound. Understanding the way medical drugs are metabolized can be used in further research for tailoring dosages for patients to maximize the effectiveness of these drugs.

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Apr 15th, 4:35 PM Apr 15th, 5:00 PM

Genetic Variation in Drug Metabolism in Relation to Age, Gender, and Ethnicity

Guzman 114

Drug metabolism is a key part in effectiveness of medications, and more recent studies have gone further into the varying rates and factors involved in drug metabolism in patients. Variability in function has been observed among people of different genders, ages, and ethnic background. My literature review investigates case studies on abnormal breakdown of drugs observed in people sharing certain genetic polymorphisms. This is likely resulting from altered metabolic pathways for the drugs, which can slow down or speed up the breakdown of the active compound. Understanding the way medical drugs are metabolized can be used in further research for tailoring dosages for patients to maximize the effectiveness of these drugs.