A collection of Master's Theses from the Department of Natural Sciences and Mathematics at Dominican University of California.

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Theses/Capstones from 2016

Transgenerational epigenetic inheritance via environmental stress in Caenorhabditis elegans, Monica A. Arroliga

Evaluating the Performance of in Silico Predictive Models on Detecting Splice-altering Variants, Erica Cayton

Optimizing Pharmacological Lifespan Extension: Testing Chemical Compounds for Additive Effects on Longevity, Elizabeth Chao

Induction of Human Embryonic stem cell derived retinal stem cells in vitro using transient overexpression of messenger RNA for BLIMP, ONECUT1 and OTX2, Helen Cifuentes

Inhibition of MCF-7 Breast Cancer Cell Proliferation by Diarylthiourea Analogs, Maryam Fallatah

Synaptic Homeostasis at the Drosophila Neuromuscular Junction: Molecular Mechanisms and Developmental Adaptation, Lindsay A. Gray

Exploring the Role of Oxytocin Signaling in Aging Using Caenorhabditis elegans, Kandyce M. Hamilton

Integrity of the Barrier Epithelium in Drosophila Gut is Mediated by Factors That Regulate Intestinal Stem Cell Activity, Adam A. Kinion

Rac1 and IRE1 are Required to Prevent Early Loss of Intestinal Homeostasis in Drosophila melanogaster, Mauricio M. Ortega

Modeling Therapeutic Strategies for Diabetic Pathologies, Alexander Rifkind

Evaluation of Seizure Threshold as an Early Behavioral Marker of Disease Progression in the Mouse Model of Mucopolysaccharidosis IIIA, Pamela Santiago

Targeting Estrogen Receptor Negative Breast Cancer Cells Using Diarylthiourea Analogs of SHetA2, Hongye Zou

Theses/Capstones from 2015

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Investigating Potential Therapies to Decrease the Rate of Cystine Stone Growth in Slc3a1-/- Mice, Sruthi Damodar

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Investigation of Dual Stage Acridones as a Potent Malaria Treatment, Stephanie Huezo

Modeling Uric Acid Kidney Stones Disease in D. melanogaster using RNAi and Dietary Modulation, Hai T.H. Lu

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Proteins Involved in HDACi Induced Decay of ERBB2 Transcripts in Breast Cancer, Sadaf Malik

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Ectodomain Mutations Alter the Proteolysis of the Amyloid-β Precursor Protein (APP), Michael S. Mitsumori

Efficient In Vitro Development of Photoreceptors from Human Pluripotent Stem Cells, Joseph C. Reynolds

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Development of Quantitative Tools for the Characterization and Analysis of the Blood Brain Barrier in Normal and MPS IIIB Mice, Sara M. Rigney

Theses/Capstones from 2014

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Neural Stem Cells as a Model to Study Huntington’s Disease, Rawan Bakhsh

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Evaluation of Select Publicly Available in Silico Methods for Predicting Functional Effects of Missense Mutations in the GALNS Gene, Kathryn Davidson

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MicroRNA Expression Signature of Retinal Pigmented Epithelial Cells Associated with the Phenotype of Age-Related Macular Degeneration, Mark Anthony Gutierrez

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Consequences of Endogenous Mitochondrial Oxidative Stress in the Heart, Kristin Alisha Koenig

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Application of High-Performance Liquid-Chromatography Mass-Spectrometry Platform to Study Metabolism and Epigenetic Control of Metabolism, Kylie Patricia Mitchell

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Effects of Heregulin on Muscle: A Biochemical and Histological Analysis, Nicole Justine Moss